Thermo Scientific License Manager

About Thermo Scientific License Manager

The Thermo Scientific ™ product license you have acquired defines your rights to use Thermo Scientific applications and their modules (extensions) with a specific level of functionality, for a certain version, on designated equipment, and for a specific number of simultaneous users. Additionally, the license can be restricted to a specific period of time or to specific use cases.

Your product license is protected by a license key. Each time the application is launched, it checks for a valid license key. If a valid license key is found, the application runs. Otherwise, you are requested to get a valid license key.

Thermo Scientific products have separate license keys for all editions and extensions.

Local (Node-locked) versus Floating licenses

There are two main types of licenses: local licenses, also called node-locked licenses, and floating licenses.

Local licensing allows the software to run on a single, identified computer only.

If you have purchased floating licenses, one or several concurrent users can run sessions at the same time from their computers located on your local network. The number of concurrent users equals the number of tokens purchased. To use floating licenses, you must install FlexNet Publisher license server manager on a local server. Then, on each end user’s computer, you need to specify the location of this local licensing server (see License server configuration).

If you have purchased floating licenses, you should have received an email from FRBOR.3d_license@thermofisher.com containing instructions to set up the license server and activate the product on the end user’s computer. Please follow those instructions, or contact your local license administrator for additional information.

Time-limited versus Perpetual licenses

Licenses can be time-limited or perpetual. Time-limited licenses are valid until a given date, which is shown in the product splash screen at start up or in the About dialog (accessible from the Help › About menu). After this date, Thermo Scientific software will stop working. This is usually the case for trial licenses, Beta licenses, or renewable rented licenses (i.e., yearly subscriptions).

License Manager Actions

When you launch a Thermo Scientific product for the first time, you should be redirected to a display which indicates that no product is activated on your computer (Fig. 1).

– No product is activated

Click Activate license(s). This opens a page where you choose which activation method to use (Fig. 3).

If Thermo Scientific products already have been activated on your computer, displays the Licenses screen (Fig. 2), listing all activated products.

– Licenses screen

To select which activation method to use, click the Activate button at the top right of the Licenses screen period (Fig. 2).

Once in the Activation methods display (Fig. 3):

  • Select Activation code to enter the received activation code of the purchased product, with an online or offline option depending to the availability of an internet connection on your computer.
  • Select License server to use a Flexnet license server (License server configuration).
– Activation methods display

Online Local Activation

When you work in local activation, allows you to manage your licenses.

Note: An Internet connection is required for all following actions. If you do not have Internet connection, refer to the Offline Local Activation.

Activate Local License(s) – Online

After purchasing one or more licenses, you will receive an email from FRBOR.3d_license@thermofisher.com containing a set
of activation codes for each product or option purchased.

  • Launch Thermo Scientific License Manager.
    • If you have not activated any product, indicates that no product is activated on your computer (Fig. 1). Click Activate license(s).
    • If you already have one or more products activated on your computer, lists the products that are activated (Fig. 2) Click on the Activate button on the top right of the display.
  • In the Activation methods screen (Fig. 3), click Activation mode and then Online Activation.
  • In the Activate License(s) screen (Fig. 4), copy and paste your activation codes into the provided text field and click Activate.
– Activate license(s) display

A connection to the online activation server starts immediately. When the activation is complete, the product is ready to be used and the license manager displays information related to the activation.

Deactivate Local License(s) – Online

If you want to deactivate a local license:

  • Launch Thermo Scientific License Manager.
  • In the Licenses screen (Fig. 2), select Deactivate either for an entire suite of product licensesor for the license you want to deactivate, click on the icon.
  • In the Deactivation mode display (Fig. 5), click Online deactivation.
  • In the Deactivate License(s) display (Fig. 6), confirm the deactivation by clicking the Continue button.
– Deactivation mode display
– Deactivate License(s) display

Reactivate Local License(s) – Online

Thermo Scientific software can be sold as yearly renewable subscriptions. These licenses are time-limited and will expire, usually after one year (Fig. 7).

– Expired licenses screen

If you want to reactivate a local license:

  • Launch Thermo Scientific License Manager.
  • In the Expired licenses screen (Fig. 7), select Reactivate either for a multiple list of product licenses
    or for the expired license you want to reactivate, click the icon.
  • In the Reactivation mode display (Fig. 8), click Online reactivation.
  • In the Reactivate License(s) display (Fig. 9), confirm the reactivation by clicking the Continue button.
– Reactivation mode display
– Reactivation License(s) display

Upgrade Local License(s) – Online

When a new version of a Thermo Scientific Software application is released, you will need to upgrade your activated licenses.

Licenses screen
– Licenses screen

If you want to upgrade a local license:

  • Launch Thermo Scientific License Manager.
  • In the Licenses screen (Fig. 10), select Upgrade either for a multiple list of product licensesUpgrade product

    or for the license you want to upgrade, click the Upgrade button icon.

  • In the Upgrading mode display (Fig. 11), click Online upgrading.
  • In the Upgrade License(s) display (Fig. 12), confirm the upgrade by clicking the Continue button.
Upgrade wizard
– Upgrading mode display
Upgrading license table
– Upgrading License(s) display

Offline Local Activation

In offline activation mode, you are able to perform the same actions described in Online Local Activation Mode but without having an Internet connection on the machine where the license is installed.
Note that Internet access from another machine is still required to complete offline activation.

Note: Access to a computer with an internet connection is required.

Activate Local License(s) – Offline

When you purchase one or more product licenses (editions and/or extensions), you should receive an email from FRBOR.3d_license@thermofisher.com containing a set of activation codes for each purchased product or option.

  • Launch Thermo Scientific License Manager.
    • If you do not yet have any product activated yet, indicates that no product is activated on your computer (Fig. 1). Click Activate license(s).
    • If you already have some products activated on your computer, lists the products that are activated on your computer (Fig. 2). Click Activate button at the top right of the display.
  • In the Activation mode display (Fig. 3), click Offline Activation.
  • In the Activate License(s) display, copy and paste your activation codes into the provided text field and click Activate.

Follow these steps for an offline activation:

  • Click Create request file in the Offline license Activation (1/3) screen (Fig. 13).
  • Specify where to save the request.tlm file that contains your offline activation request, then click Save.
  • Transfer your TLM request file to a computer with an Internet connection.
  • On the computer with an Internet connection, open https://tlm-portal.com/operation in a web browser.
  • Select Upload File
  • Click the Choose file button, select your TLM request file then click Open button.
  • Click Submit. This initiates the download of the response.tlm file. Specify a location to save it.
  • Transfer the response.tlm file to the computer where you want the local license to be activated.
  • In the Offline license activation (2/3) display (Fig. 14), click Finish now.
  • In the Offline license activation (3/3) display (Fig. 15), click Load response file.
  • Navigate to and select the response.tlm file, then click Open button.
– Offline license activation (1/3)
– Offline license activation (2/3)
– Offline license activation (3/3)

When activation is complete, the product is ready to be used and the displays information related to the activation.

Deactivate Local License(s) – Offline

If you want to deactivate a local license:

  • Launch Thermo Scientific License Manager.
  • In the Licenses screen (Fig. 2), select Deactivate either for a multiple list of product licensesor for the license you want to deactivate, click the icon.
  • In the Deactivation mode display (Fig. 5), click Offline deactivation.
  • In the Deactivate License(s) display (Fig. 6), confirm the deactivation by clicking the Continue button.

Follow these steps for an offline deactivation:

  • Click Create request file in the Offline license Deactivation (1/3) screen (Fig. 16).
  • Specify where to save the request.tlm file that contains your offline activation request, then click Save.
  • Transfer your TLM request file to a computer with an Internet connection.
  • On the computer with an Internet connection, open https://tlm-portal.com/operation in a web browser.
  • Select Upload File
  • Click the Choose file button, select your TLM request file then click Open button.
  • Click Submit. This initiates the download of the response.tlm file. Specify a location to save it.
  • Transfer the response.tlm file to the computer where you want the local license to be deactivated.
  • In the Offline license deactivation (2/3) display (Fig. 17), click Finish now.
  • In the Offline license deactivation (3/3) display (Fig. 18), click Load response file.
  • Navigate to select the response.tlm file, then click Open button.
– Offline license deactivation (1/3)
– Offline license deactivation (2/3)
– Offline license deactivation (3/3)

Reactivate Local License(s) – Offline

Thermo Scientific software can be sold as yearly renewable subscriptions. These licenses are time-limited and will expire, usually after one year (Fig. 7).

If you want to reactivate a local license:

  • Launch Thermo Scientific License Manager.
  • In the Expired licenses screen (Fig. 7) select Reactivate either for a multiple list of product licenses
    or for the expired license you want to reactivate, click the icon.
  • In the Reactivation mode display (Fig. 8), click Offline reactivation.
  • In the Reactivate License(s) display (Fig. 9), confirm the reactivation by clicking on Continue button.

Follow these steps for an offline reactivation:

  • Click Create request file in the Offline license Reactivation (1/3) screen (Fig. 19).
  • Specify where to save the request.tlm file that contains your offline activation request, then click Save.
  • Transfer your TLM request file to a computer with an Internet connection.
  • On the computer with an Internet connection, open https://tlm-portal.com/operation in a web browser.
  • Select Upload File
  • Click the Choose file button, select your TLM request file then click Open button.
  • Click Submit. This initiates the download of the response.tlm file. Specify a location to save it.
  • Transfer the response.tlm file to the computer where you want the local license to be reactivated.
  • In the Offline license reactivation (2/3) display (Fig. 20), click Finish now.
  • In the Offline license reactivation (3/3) display (Fig. 21), click Load response file.
  • Navigate to select the response.tlm file, then click Open button.
– Offline license reactivation (1/3)
– Offline license reactivation (2/3)
– Offline license reactivation (3/3)

Upgrade Local License(s) – Offline

When a new version of a Thermo Scientific Software application is released, you will need to upgrade your activated licenses.
Important: upgrades in offline mode are only available for licenses in version 2021.1 or later. Before upgrading, you must activate the license codes you have received by email when the version 2021.1 was released.

If you want to upgrade a local license:

  • Launch Thermo Scientific License Manager.
  • In the Licenses screen (Fig. 2), select Upgrade either for a multiple list of product licensesUpgrade product

    or for the license you want to upgrade, click the Upgrade button icon.

  • In the Upgrading mode display (Fig. 11), click Offline upgrading.
  • In the Upgrading License(s) display (Fig. 12), confirm the upgrading by clicking the Continue button.

Follow these steps for an offline upgrading:

  • Click Create request file in the Offline license Upgrading (1/3) screen (Fig. 22).
  • Specify where to save the request.tlm file that contains your offline upgrading request, then click Save.
  • Transfer your TLM request file to a computer with an Internet connection.
  • On the computer with an Internet connection, open https://tlm-portal.com/operation in a web browser.
  • Select Upload File
  • Click the Choose file button, select your TLM request file then click Open button.
  • Click Submit. This initiates the download of the response.tlm file. Specify a location to save it.
  • Transfer the response.tlm file to the computer where you want the local license to be upgraded.
  • In the Offline license upgrading (2/3) display (Fig. 23), click Finish now.
  • In the Offline license upgrading (3/3) display (Fig. 24), click Load response file.
  • Navigate to select the response.tlm file, then click Open button.
Offline upgrading
– Offline license upgrading (1/3)
Offline upgrading upload
– Offline license upgrading (2/3)
Offline upgrading load
– Offline license upgrading (3/3)

License server configuration

When you are working with floating licenses, you generally have an external server with all the floating licenses to use. To configure a server,
from the Activation methods display (Fig. 3), select License server.

You are redirected to the license server display (Fig. 25) where you have to enter the server name (or its IP address) followed by a port if there is a specific one (if not specified, the default port value is 27000):


<server_name|IP>:<port>

– License server display

By clicking Save, the server is added to the list of available sources where to search for licenses, and is displayed on the Licenses screen.
If the server is not reachable, you are redirected to the Floating server not alive (Fig. 26) page. As shown on the page, this can be due to a firewall or a network issue.
You can then go back to edit the server configuration or save it despite the “Not Alive” status. From the Licenses screen, if the license server status is different from alive, no license will be available from it.

You can deactivate a license server by clicking the Disconnect button at the end of the license server line.

– Flexnet server not alive

License file configuration

If you have a license file to activate your application, from the Activation methods display (Fig. 3) you have to choose License file.

You are redirected to the license file display (Fig. 27) where you have to enter the license file content (copy/paste the license file content into the provided text field):

– License file display

Click the Activate button, you are redirected to the Licenses screen and the activated products are identified as LICENSE_FILE.
As for other licenses, you can deactivate a license from a license file by clicking the Deactivation button at the end of the license line.

View information on a Local License

To get information on a specific license, from the Licenses screen, click the product name for which you want more information. This opens the License Information display (Fig. 28).

– License information

Transferring Local License(s) to a New Computer

After activating a local license on a computer, you might want to move it to a new one. To do so, you first need to de-activate the first license by returning the associated activation code and then activate it again on the new computer:

  • On the old computer, follow Deactivation procedure, either online or offline , to return local license(s) so they can be activated on another system.
  • When deactivating the license(s), be sure to keep a copy of the corresponding Activation code(s): use the Copy all to clipboard button (Fig. 29) to copy the deactivated activation code(s).
  • On the new computer, follow Activation procedure for local license(s), either online or offline , and activate the activation code(s) copied to clipboard.
Deactivation license table
– Deactivate License(s) display

Licensing Troubleshooting

JavaScript errors when running the License Manager

If you encounter some JavaScript errors when running the License Manager or activating your licenses,  please try to run the Thermo Scientific License Manager with administrator rights to solve the issue.

Deactivating a License

When using license activation codes, deactivate them before any of the following operations:

  • Uninstalling
  • Reinstalling or replacing the operating system
  • Replacing the hard drive
  • Disposing of the system

Otherwise, you will not be able to reactivate them on another system because they will still be active on the original system, and it will be difficult or impossible for you to deactivate them for a transfer.

To deactivate a license, follow the instructions according to your licensing mode: online or offline.

Firewall Problem

If you have an Internet connection and encounter the “Unable to connect to server https” error when trying to activate a license, this is caused by your firewall configuration.

You need to configure your firewall to allow the connection to the online activation server. For example:

Return impossible with Local License

The License Manager uses the Unique Machine Number (UMN) to validate the identity of the machine that initiated the request.
The Unique Machine Number value is retrieved from your system hardware information, or from hypervisor-controlled information for virtual machines.
If your system hardware is modified since the original activation, the UMN of your machine can be changed and the License Manager will consider your
machine to be a different machine. Consequently, the following error message may appear:


"Trying to return a fulfillment issued to a different machine."

If this error message occurs, contact Technical Support for assistance. See “Contact and Support”.

Contact and Support

For technical support, contact
FRBOR.3d_hotline@thermofisher.com
For requesting license keys, contact
FRBOR.3d_license@thermofisher.com